How to Use the iS Clinical Active Peel System at Home

By Art of Skin Care | Published: 2026-10-27

Category: How-to Guides

Learn how to safely use the iS Clinical Active Peel System for a professional-quality at-home chemical peel. Step-by-step instructions, common mistakes, and tips for best results.

Quick answer

Use the iS Clinical Active Peel System once a week for 30 days: prep clean skin, apply peel solution evenly, wait 5–10 minutes, neutralize with the included post-peel cloth, and follow with a gentle moisturizer.

Why choose a 30-day at-home peel system

The iS Clinical Active Peel System combines glycolic acid, DNA repair enzymes, and peptides to resurface texture, fade pigmentation, and firm skin over a month-long protocol. Unlike single-use peels, this system is designed for gradual improvement with less irritation risk.

Because it is an at-home system, you control the frequency and intensity. The trade-off is that results appear more slowly than a single in-office peel, but the lower downtime makes it easier to fit into a weekly routine.

Step-by-step instructions for using the iS Clinical Active Peel System

Step 1: Prep your skin: Wash your face with a gentle, non-exfoliating cleanser and pat dry. Do not apply any other products (serums, retinoids, or acids) before the peel. Skipping the cleanse or applying other actives can cause uneven absorption or irritation.
Step 2: Apply the peel solution: Saturate the provided applicator pad with the peel solution. Sweep it evenly over your face and neck, avoiding the eye area, lips, and any broken skin. Use gentle, upward strokes. Overlapping passes can concentrate acid in one spot and cause a patchy result.
Step 3: Wait and monitor: Leave the peel on for 5 to 10 minutes. You may feel a mild tingling or warmth. If you experience stinging or discomfort, rinse immediately with cool water. Start with 5 minutes for your first use and increase gradually. Do not leave it on longer than 10 minutes.
Step 4: Neutralize and remove: Use the included post-peel cloth to gently wipe off the solution. Follow the system’s instructions for neutralizing — some versions require a specific wipe, others just water. Pat dry. Do not rub the cloth harshly; the skin is more vulnerable after the peel.
Step 5: Moisturize and protect: Apply a gentle, fragrance-free moisturizer to calm the skin. For the next 24 hours, avoid other exfoliants, retinoids, and direct sun exposure. Use SPF 30+ daily. Skipping sunscreen after a peel increases the risk of pigmentation changes.

Product facts

iS Clinical Active Peel System: A 30-day at-home peel system with glycolic acid, DNA repair enzymes, and peptides to resurface texture, fade pigmentation, and firm skin. Glycolic acid exfoliates the surface while enzymes and peptides support repair, making it suitable for targeting both texture and signs of aging in one routine.
iS Clinical Active Peel System